Howard S. Kaufman, MD, MBA

Dr. Kaufman is an Associate Professor of Surgery and Obstetrics and Gynecology at the Keck School of Medicine of the University of Southern California. He serves as Chief of the Division of Colorectal and Pelvic Floor Surgery, as well as, Chief of General Surgery at USC University Hospital.

Dr. Kaufman has clinical expertise in treating patients with pelvic floor dysfunction, as well as expertise in a variety of benign and malignant diseases of the colon, rectum, and anus including cancer, ulcerative colitis, constipation, incontinence, and diverticulitis. He is a member of the USC Bariatric Program and offers open and laparoscopic surgical options to patients suffering from morbid obesity. He also performs laparoscopic and robotic surgery for other abdominal and pelvic disorders.

Patients with pelvic floor dysfunction are treated with a multidisciplinary approach. The team of specialists treating this patient population is led by Dr. Kaufman, with collaboration from gynecology, urology, gastroenterology, behavioral sciences, physical therapy, and radiology.

Dr. Kaufman’s primary clinical and research interests are in multimodality treatment of rectal cancer, the multidisciplinary treatment of pelvic floor disorders, and the correlation between obesity and pelvic floor dysfunction.

Dr. Kaufman graduated Phi Beta Kappa from Haverford College where he earned his bachelor’s degree in Biology and Physics. He attended the Johns Hopkins School of Medicine and did his surgical training, research fellowship, and fellowship in alimentary tract surgery at the Johns Hopkins Hospital. Dr. Kaufman remained on the faculty of The Johns Hopkins School of Medicine, and held a triple appointment as Associate Professor in the Departments of Surgery, Gynecology and Obstetrics, and Oncology, until 2002. His colorectal training included study under the mentorship of Professor Neil Mortensen, Director of the Colorectal Unit at Oxford University, as well as a colorectal experience during his Johns Hopkins fellowship. Dr. Kaufman pursued an MBA degree at the Johns Hopkins University, culminating his studies at the USC Marshall School of Business and the School of Planning, Policy, and Development at University Park. He received his degree in May 2004.

He is a member of several national societies including The American Society of Colon and Rectal Surgeons, The Society of American Gastrointestinal Endoscopic Surgeons, The Association for Academic Surgery, The Society for Surgery of the Alimentary Tract, and is a fellow of The American College of Surgeons and the Society of Surgical Oncology.

Patients are seen at the Healthcare Consultation I building, adjacent to USC University Hospital.

Center for Colorectal and Pelvic Floor Disorders
1510 San Pablo Street
Suite 514
Los Angeles, CA 90033
Phone: (323) 442-6860
Fax: (323) 442-5756

A. Information:

Name in Full
Howard Scott Kaufman

Business Address
Department of Surgery
Colorectal & Pelvic Floor Surgery
1450 San Pablo Street, Suite 5400
Los Angeles, CA 90033

Business Phone: (323) 442-6860
Business Fax: (323) 442-5756

B. Education:

High School
Cherry Hill High School West, Cherry Hill, NJ, 1980

College
Haverford College, Haverford, PA, B.S. Biology and Physics, 1984

Medical School
The Johns Hopkins University School of Medicine, Baltimore, MD, 1988

University
The Johns Hopkins University MBA Program: The Business of Medicine, 1997-2004

Internship
The Johns Hopkins Hospital, Intern in Surgery 1988-89

Residencies

• The Johns Hopkins Hospital, 1989-90, Junior Resident in Surgery
• The Johns Hopkins Hospital, 1992-94, Senior Resident in Surgery
• The John Radcliffe Hospital, 1994, Registrar in Surgery
  Colorectal Surgery Unit, Oxford, England
• The Johns Hopkins Hospital, 1994-95, Chief Resident in Surgery

Fellowships

• Research Fellow, 1990-92, The Johns Hopkins Hospital, Department of Surgery
• Fellow in Surgery, 1988-95, The Johns Hopkins University School of Medicine
• Fellow in Alimentary Tract Surgery, 1995-96, The Johns Hopkins University School of Medicine, Instructor in Surgery
• Laparoscopic Bariatric Comprehensive Training Program, Laparoscopic Bariatric Specialists, 2004, Bellflower Medical Center, Bellflower, CA

Honors

• Phi Beta Kappa, Departmental Honors in Biology, Haverford College, 1984
• Alpha Omega Alpha, The Johns Hopkins University School of Medicine, 1995

Awards

• W. Barry Wood Medical Student Research Award, The Johns Hopkins University School of Medicine, 1988
• Resident’s Clinical Research Award, American College of Surgeons, Maryland Chapter, 1991
• George D. Zuidema Surgical Research Award, The Johns Hopkins University School of Medicine, 1992
• Upjohn Achievement Award for Clinical Research, Sinai Hospital of Baltimore and The Johns Hopkins University School of Medicine, 1993

Licensure:
1990-2002 - Maryland State License
2002 – California State License

Board Certification
1996 - Diplomat American Board of Surgery

C. Professional Background:

Academic Appointments

• Instructor in Surgery, The Johns Hopkins University School of Medicine, 1995-96
• Assistant Professor of Surgery, The Johns Hopkins University School of Medicine, 1996
• Secondary appointment, Assistant Professor of Gynecology and Obstetrics The Johns Hopkins University School of Medicine, 1999
• Associate Professor of Surgery and Gynecology and Obstetrics, The Johns Hopkins University School of Medicine, 2000
• Triple appointment, Associate Professor of Oncology, The Johns Hopkins University School of Medicine, 2001
• Visiting Associate Professor of Surgery, Keck School of Medicine, University of Southern California, July 2002-June 2004
• Associate Professor of Surgery, Keck School of Medicine, University of Southern California, June 2004-present
• Associate Professor of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, June 2004-present

Clinical Appointments

• Assistant Chief of Service, Department of Surgery, The Johns Hopkins Hospital, 1995-96
• Active Staff, Department of Surgery, The Johns Hopkins Hospital, 1996-2002
• Chief, Division of Colorectal and Pelvic Floor Surgery, The Keck School of Medicine, University of Southern California, July 2002
• Attending Surgeon, USC University Hospital
• Attending Surgeon, USC and LAC Medical Center
• Attending Surgeon, Kenneth Norris Jr. Cancer Hospital
• Active Staff, Kaiser Permanente, West Los Angeles, 2003-present
• Staff, Bellflower Medical Center, Bellflower, CA, 2004-present
• Provisional Staff, Huntington Memorial Hospital, Pasadena, CA, 2004-
• Chief, General Surgery, USC University Hospital, 2004-

Specific Teaching Responsibilities

The Johns Hopkins University School of Medicine and Johns Hopkins Hospital

Department of Surgery

• Lectures on inflammatory bowel disease and benign anorectal conditions to junior and senior medical students, 1996-2002
• Morbidity and Mortality Conference, Weekly, 1996-2002
• Presentations at Surgical Grand Rounds, Yearly, 1996-2002
• Attending Surgeon, Johns Hopkins Hospital
  • Daily informal teaching of residents, fellows, and medical students in operating room, clinic, endoscopy suite and anorectal physiology laboratory, 1996-2002

University

• Preceptor – Introduction to Clinical Medicine for freshmen medical students, 1999-2001
• Assistant Course Director – The Johns Hopkins Medical Institutions Annual Houston Everett Memorial Course on Urogynecology, 2000-2002
• Course Faculty – The Johns Hopkins Medical Institutions Semi-annual Course in Perioperative Management – Lectures on preoperative nutrition and laparoscopic surgery.

Other Informal/Formal Teaching Conferences at the Johns Hopkins Hospital

• Multidisciplinary Pelvic Floor Disorders Conference (Co-Chair), Bi-weekly 1997-2002
• Multidisciplinary Esophageal Cancer Treatment Group, Bi-weekly, 1997-2000
• Colorectal Cancer Conference, Weekly, 1996-2002

The Johns Hopkins University School of Nursing
Lectures on acute gastrointestinal disease to acute care nurse practitioner students, 1996-2001

Keck School of Medicine, The University of Southern California

Department of Surgery

• Division of Colorectal and Pelvic Floor Surgery Staff and Teaching Conference, Weekly, 2002-Present
• Surgical Skills Laboratory, 6 core sessions, 2002-Present
• Morbidity and Mortality Conference, Weekly, 2002-Present
• Multidisciplinary Pelvic Floor Disorders Conference - Biweekly, 2003-Present
• Bariatric Surgery Program Conference - Weekly, 2003-Present
• Attending Surgeon, USC + LAC Medical Center, USC University Hospital, USC Norris Cancer Hospital, 2002-Present
  - Daily informal teaching of residents, fellows, and medical students in operating room, clinic, endoscopy suite and anorectal physiology laboratory, 2002-Present
• Presentation at Surgical Grand Rounds, 2003
• Presentation at OB/GYN Grand Rounds, 2003
• Presentation at GI Medicine Grand Rounds, 2003

University

• Lectures on pelvic floor disorders to USC Community Hospital Network, 2003, 2004
• Lectures on colorectal cancer screening and virtual colonoscopy to USC Community Hospital Network, 2003
• Lectures on surgical options for morbid obesity to USC Community Hospital Network, 2004

Specific Administrative Responsibilities

• Physician Advisor to Performance Improvement Committee, The Johns Hopkins Hospital, 2001-2002
• Chairman of the Clinical Performance Improvement Committee for the Department of Surgery, The Johns Hopkins Hospital, 2001-2002
• Director, Anorectal Physiology Laboratory, The Johns Hopkins Hospital, 1999-2002
• Co-Director, Pelvic Floor Disorders Center, The Johns Hopkins Hospital, 1997-2002
• Chief, Division of Colorectal and Pelvic Floor Surgery, The Keck School of Medicine, University of Southern California, July 2002 – present
• Director, Anorectal Physiology Laboratory, USC University Hospital, July 2002 – present
• Director, Pelvic Floor Disorders Center, USC University Hospital, September 2002 – present
• GI Lab Committee, USC University Hospital, 2003-Present
• Chief, General Surgery, USC University Hospital, 2004-present
• Executive Peer Review Committee, USC University Hospital, 2004-present
• Performance Improvement Committee, USC University Hospital, 2004-present
• Operating Room Committee, USC University Hospital, 2004-present

Other Employment

• Laboratory manager, Electron Microscopy Service Laboratories, Inc, 1981-84
• Senior microscopist and consultant, Electron Microscopy Service Laboratories, Inc., 1981-86
• Environmental consultant, Environmental Testing and Technologies, Inc.1981-88
• Director, Environmental Testing and Technologies, Inc., 1984-88

Committee Memberships

University

• Medical School Council, The Johns Hopkins University School of Medicine, 1999-2001
• Physical Medicine/Rehabilitation Search Committee, The Johns Hopkins University School of Medicine, 2001-2002

National

• Steering Committee, Genzyme Corporation, Sponsor: A prospective, randomized, multicenter, controlled evaluation of the efficacy and safety of Seprafilm bioresorbable membrane in the reduction of the incidence of bowel obstruction in general surgery, 1999-present
• Technologies Committee, The American Society of Colon and Rectal Surgeons, 1999-2002
• Steering Committee, Pelvic Floor Disorders Treatment Network, National Institutes of Health, National Institute of Child Health and Human Development (NICHD), 2001
• Steering Committee, Volunteer Medical Staff, The 2002 US Senior Open, Caves Valley Golf Club, Owings Mills, MD

D. Society Memberships:

National

• The Johns Hopkins Medical and Surgical Association, 1988
• Association for Academic Surgery, 1996
• Society for Surgery of the Alimentary Tract, 1997
• American Society of Colon & Rectal Surgeons, Member, 1997
• Society of Surgical Oncology, Fellow, 1997
• Society of American Gastrointestinal Endoscopic Surgeons, 1998
• American College of Surgeons, Fellow, 1997
• American Urogynecologic Society, 1997
• American Society for Bariatric Surgery, 2004

E. Consultantships

Editorial Review: Journals--Outside Reviewer:

• Scanning Microscopy
• Diseases of the Colon and Rectum
• Journal of Pelvic Surgery
• Journal of Surgical Research
• Journal of Urology
• Surgery

Scientific Advisory Board – Calypso Medical, Inc.

F. Research Activities

Major Areas of Research Interest

• Diagnosis and management of pelvic floor disorders
• Multimodality treatment of rectal cancer, other pelvic malignancies
• The effects of specialization on outcomes in the treatment of colorectal diseases and pelvic floor disorders
• Development and testing of a surgical navigation system for localization of soft tissue tumors
• “Bloodless” surgery – advanced transfusion practices
• Adhesion prevention following colorectal surgery

Research in Progress

• Evaluation of the role dynamic MR imaging in the management of pelvic floor disorders
• Prospective evaluation of the abdominal sacral colpoperineopexy with rectopexy (+/- sigmoid colon resection) for the treatment of perineal descent with defecatory dysfunction
• Prospective evaluation of the choice of graft material for use in the abdominal sacral colpopexy for the treatment of perineal descent
• Prospective RCT of the effect of Seprafilm in the prevention of intestinal obstruction following colorectal surgery
• Prospective RCT of the use of RF energy (Secca procedure) in the treatment of fecal incontinence
• Retrospective evaluation of the effect of multidisciplinary treatment of advanced pelvic malignancies
• Prospective evaluation of the effect of neoadjuvant chemoradiation for the treatment of advanced rectal cancer in the era of total mesorectal excision
• Preclinical testing of a surgical navigation system for the localization of soft tissue tumors

Research Grants in Past Five Years

1. Transferrin, Iron Deficiency and Gallstone Pathogenesis
   National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) RO1
   1997-2000 Collaborator (Henry A. Pitt, M.D., P.I.)
   $1,164,523

2. Age-related changes in the female pelvic floor
   A dynamic MR-Imaging Study
   The Johns Hopkins Fund for Medical Discovery
   1997 PI
   $14,600

3. A prospective, randomized, multicenter, controlled evaluation of the efficacy safety of Seprafilm bioresorbable membrane in the reduction of the incidence bowel obstruction in general surgery
   Genzyme Corporation
   1998 PI for Johns Hopkins
   $ 90,540

4. Cholecystokinin-octopeptide for the Prevention of Gallbladder
   Stasis and Sludge in Bone Marrow Transplant Patients.
   Johns Hopkins Oncology Center
   1999 Co-Investigator (PI: Linda Lee, M.D.)
   $39,920

5. A Phase III, controlled, open label, multi-center, parallel group study designed to evaluate the safety and efficacy of Poly SFH-P Injection in the total elimination of allogeneic red cell transfusion
   Sponsor: Northfield Laboratories Inc., Evanston, IL
   1998-2001 Co-Investigator (PI, Edward J. Norris, M.D., M.B.A.)
   $393,000

6. The multi-centered evaluation of the safety and efficacy of PolyHemel [Poly SFH-P Injection (polymerized human hemoglobin, pyridoxylated] in acute blood loss
   Northfield Laboratories Inc., Evanston, IL
   2000-2001 Co-Investigator (PI: Edward J. Norris, M.D., M.B.A.)
   $286,000

7. A phase 2, single-blind, randomized, controlled, dose-escalation safety study of AF0144 (perflubron emulsion) as a temporary intravenous oxygen carrier in subjects undergoing high-blood-loss elective non-cardiac surgery
   Alliance Pharmaceutical Corp.
   2000-2001 Co-Investigator (P I: Edward J. Norris, M.D., M.B.A)
   $152,370

8. Clinical utility of blood volume assessment in the perioperative period
   Daxor Corporation
   2000 Co-Investigator (P I: Edward J. Norris, M.D., M.B.A.)
   $86,000

9. Pelvic Floor Disorders Treatment Network
   National Institutes of Health
   National Institute of Child Health and Human Development (NICHD)
   2000-2001 Co-Investigator
   Principal Investigator: Geoffrey Cundiff, M.D.

10. Intra-operative localization of Implanted Beacons in Soft Tissue
    Calypso Medical, Inc.
    2001 PI
    $2,000

11. Stability of Implanted Beacons in Soft Tissue
    Calypso Medical, Inc.
    2001 PI
    $2,000

12. A multi-center, randomized, double blind, sham-controlled trial investigating sub mucosal delivery of radio frequency energy to the anal canal (The Secca Procedure) for the treatment of fecal incontinence.
    Curon Medical, Inc.
    2002 PI for Johns Hopkins
    $75,000

13. InterStim Sacral Nerve Stimulation Therapy for Bowel Control
    Fecal Incontinence Study
    Medtronic, Inc.
    2003 PI for USC
    $93,000
    

1. Frasca P, Galkin B, Muir H, Soriano R, and Kaufman HS: A new method of magnifying photographic images using the scanning electron microscope in the backscattered electron mode. Scanning Electron Microscopy 3:917-923, 1982.

2. Loewy AG, Wilson FJ, Taggert NM, Greene EA, Frasca P, Kaufman HS and Sorrell MJ: A covalently cross-linked matrix in skeletal muscle fibers. Cell Motility 3:463-483, 1983.

3. Kaufman HS, Magnuson TH, Lillemoe KD, Frasca P, and Pitt HA: The role of bacteria in gallbladder and common duct stone formation. Ann Surg 209:584-592, 1989.

4. Kaufman HS, Lillemoe KD, Magnuson TH, Frasca P, and Pitt HA: Backscattered electron imaging and windowless energy dispersive x-ray microanalysis: A new technique for gallstone analysis. Scanning Microscopy 4:856-862, 1990.

5. Kaufman HS, Magnuson TH, Webb TH, Watt PC, Fox-Talbot MK, Pitt HA, and Lillemoe KD: Bilirubin monoglucuronide promotes cholesterol gallstone formation. J Surg Res 50:504-509, 1991.

6. Magnuson TH, Ahrendt SA, Lillemoe KD, Kaufman HS, Watt PC, and Pitt HA: Short-term fasting increases biliary calcium and bilirubin. J Surg Res 50:524-534, 1991

7. Ahrendt SA, Fox-Talbot K, Kaufman HS, Lipsett PA, Lillemoe KD, Pitt HA: Are vesicles required for nucleation of cholesterol monohydrate crystals? Surg Forum 42:190-192, 1991.

8. Kaufman HS, Lipsett PA, Fox-Talbot MK, Shermak M, Lillemoe KD, and Pitt HA: Cholesterol feeding promotes hepatic secretion of glycoproteins in gallbladder. Surg Forum 43:178-180, 1992.

9. Ahrendt SA, Fox-Talbot MK, Kaufman HS, Lillemoe KD and Pitt HA: A novel cholesterol carrier helps prevent crystal precipitation. Surg Forum 43:1854-185, 1992.

10. Kaufman HS, Ahrendt SA, Pitt HA and Lillemoe KD: The effect of erythromycin on motility of the duodenum, sphincter of Oddi and gallbladder in the prairie dog. Surgery 114:543-548, 1993.

11. Kaufman HS, Shermak MA, May CA, Pitt HA, and Lillemoe KD: Nitric oxide inhibits resting sphincter of Oddi activity. Am J Surg 165:74-80, 1993

12. Lipsett P, Hildreth J, Kaufman HS, Lillemoe KD, and Pitt HA: Human gallstones contain pro-nucleating nonmucin glycoproteins that are immunoglobulins. Ann Surg 219:25-33, 1993.

13. Lillemoe KD, Cameron JL, Kaufman HS, Yeo CJ, Pitt HA, and Sauter PK: Chemical splanchnicectomy in patients with unresectable pancreatic cancer: A prospective randomized trial. Ann Surg 217:447-457, 1993.

14. Cameron JL, Pitt HA, Yeo CJ, Lillemoe KD, Kaufman HS, and Coleman J: One hundred and forty-five consecutive pancreaticoduodenectomies without mortality. Ann Surg 217:430-435, 1993

15. Kaufman HS, Magnuson TH, Lillemoe KD, Frasca P and Pitt HA: The distribution of calcium salt precipitates in the core, periphery and shell of cholesterol, black pigment and brown pigment gallstones. Hepatology 19:1124-1132, 1994.

16. Ahrendt SA, Fox-Talbot K, Kaufman HS, Lillemoe KD, Pitt HA: Cholesterol nucleates rapidly from mixed micelles in the prairie dog. Biochem. Biophys. Acta 1211:7-13, 1994.

17. Ahrendt SA, Fox-Talbot MK, Kaufman HS, Lillemoe KD, and Pitt HA: Characterization of a small vesicular cholesterol carrier in human gallbladder bile. Ann Surg 220:635-643, 1994.

18. Barnes SA, Lillemoe KD, Kaufman HS, Sauter PK, Yeo CJ, Talamini MA, Pitt HA, and Cameron JC: Pancreaticoduodenectomy for benign disease. Am J Surg 171:131-135, 1996

19. Ratner LE, Cisek LJ, Moore RG, Cigarroa FG, Kaufman HS, and Kavoussi LR: Laparoscopic live donor nephrectomy. Transplantation 60(9):1047-1049, 1995.

20. Micali S, Silver RI, Kaufman HS, Douglas VD, Marley GM, Partin AW, Moore RG, Kavoussi LR, Docimo SG. Measurement of urinary N-Acetyl-Beta, D-Glucosaminidase to assess renal ischemia during laparoscopic operations. Surg Endosc 13:503-506, 1999.

21. Sohn TA, Lillemoe KD, Yeo CJ, Pitt HA, Kaufman HS, Hruban RH, Cameron JL: Adenocarcinoma of the duodenum: the influence of site on survival. J Gastrointestinal Surg 2:79-87, 1998.

22. Bauer JJ, Schulam PG, Kaufman HS, Moore RG, Irby PB, Kavoussi LR. Laparoscopy for the acute abdomen in the postoperative urologic patients. Urology. 51:917-9, 1998.

23. Kaufman HS, Kahn AC, Iacobuzio-Donahue C, Talamini MA, Lillemoe KD, Hamilton SR. Cytomegaloviral enterocolitis: Clinical associations and outcome. Dis Col Rectum, 42:24-30, 1999.

24. Tang DG, Bowers HM, Gordon TA, Nurse-Findley S, Choti MA, Kaufman HS, Bender JS, Harmon JW, Cameron JL. Case volume and outcomes in research for colorectal carcinoma. Surgical Forum 49:559-61, 1998.

25. Tortolani JP, Kaufman HS, Nahabedian MY, Frassica FJ. Fistula between the rectum and left pericapsular hip after adjuvant radiation and surgical therapy for rectal carcinoma: A Case Report. J Bone and Joint Surg 81-A: 1596-9, 1999

26. Alexander J, Kaufman HS, Hedican S, Hamilton SR. Adenocarcinoma in an isolated ileal sleeve 30 years after periureteral wrap. J Urology 160:1424-25, 1998.

27. Kaufman HS, Hsieh G, Gordon TA. Ureteral catheterization and outcomes in colorectal surgery. Surgical Forum 50:671-674, 1999.

28. Gordon TA, G, Hurdt JD, Kaufman HS, Magnuson TH, Cameron JL. Outcomes of gastrointestinal surgery for geriatric patients: A statewide population-based study. Surgical Forum 50:660-662, 1999.

29. Heath EI, Burtness B, Heitmiller RF, Salem R, Kleinberg L, Knisch JPS, Yang SC, Talamini MA, Kaufman HS, Canto MI, Topazan M, Wu TT, Olukayode K, Forastiere AA. Phase II evaluation of pre-operate chemoradiation and post-operate adjuvant chemotherapy for squamous cell carcinoma and adenocarcinoma of the esophagus. J Clin Oncol 18:868-76, 2000.

30. Heath EI, Talamini MA, Kaufman HS, Wheeler J, Heitmiller RF, Olukayode K, Forastiere AA. The role of laparoscopy in preoperative staging of esophageal cancer. Surg Endosc 14: 495-9, 2000.

31. Harmon JW, Tang DG, Gordon TA, Bowman HM, Choti MA, Kaufman HS, Bender JS, Duncan MD, Magnuson TH, Lillemoe KD, Cameron JL. Hospital volume can serve as a surrogate for surgeon volume for achieving excellent outcomes in colorectal resection. Ann Surg 1999; 230 (3):404-11.

32. Pannu HK, Kaufman HS, Cundiff GW, Genadry R, Bluemke DA, Fishman EK. Dynamic MR imaging of pelvic organ prolapse: Spectrum of abnormalities. Radiographics 20: 1567-82, 2000.

33. Van der Wal Bart CH, Cleffken BI, Gulec B, Kaufman HS, Choti MA. Results of salvage abdominoperineal resection for recurrent anal carcinoma following combined chemoradiation therapy. J Gastrointestinal Surgery, 2001; 5:383-7.

34. Schmidt CM, Talamini MA, Kaufman HS, Lillemoe KD, Learn P, Bayless T. Laparoscopic surgery for Crohn’s Disease: Reasons for conversion. Ann Surg 233:733-739, 2001.

35. Kaufman HS, Buller JL, Thompson JR, Pannu HK, DeMeester SL, Genadry RR, Bluemke DA, Jones B, Rychcik JL, Cundiff GW. Dynamic pelvic MR imaging and cystocolpoproctography alter surgical management of pelvic floor disorders. Dis Colon Rectum 44:1575-83; discussion 1583-4, 2001.

36. Bristow RE, Smith Sehdev AE, Kaufman HS, Montz FJ Ablation of metastatic ovarian carcinoma with the argon beam coagulator: Pathologic analysis of tumor destruction. Gynecologic Oncology 83:49-55, 2001.

37. Chen H, George BD, Kaufman HS, Malaki MB, Mortensen N, Kettlewell GW. Endoscopic transanal resection (ETAR) provides palliation equivalent to transabdominal resection in patients with metastatic rectal cancer. J Gatrointest Surg 5:282-6, 2001.

38. Becker SO, Tomacruz R, Kaufman HS, Bristow RE, Montz FJ. Gynecologic abnormalities in surgically treated women with stage II or III rectal cancer. J Am Coll Surg 194: 315-23, 2002.

39. Nilsson KR, Berenholtz SM, Dorman T, Garrett E, Lipsett P, Kaufman HS, Pronovost, PJ. Preoperative predictors of blood transfusion in colorectal cancer surgery. J Gastrointest Surg 6(5): 753-62, 2002.

40. Pannu HK, Genadry R, Gearhart S, Kaufman HS, Cundiff GW, Fishman EK. Focal levator ani eventrations: Detection and characterization by magnetic resonance in patients with pelvic floor dysfunction. Int Urogyn J Intl Pelvic Floor Dysfunction 14(2): 89-93, 2003.

41. Pannu HK, Genadry R, Kaufman HS, Fishman EK. Computed tomography evaluation of pelvic organ prolapse: techniques and applications. J Comput Assist Tomography 27(5): 779-85, 2003.

42. Bristow RE, del Carmine MG, Kaufman HS, Montz FJ. Radical oophorectomy with primary stapled colorectal anastomosis for resection of locally advanced epithelial ovarian cancer. J Am Coll Surg 197(4): 565-74, 2003.

43. Beck DE, Cohen Z, Fleshman JW, Kaufman HS, van Goor, H, Wolff, BG,. A prospective, randomized, multicenter, controlled study of the safety of Seprafilm® adhesion barrier in abdominopelvic surgery of the intestine. Dis Colon Rectum 46(10): 1310-9, 2003.

44. Sonnenday CJ, Kaufman HS. Use of an implantable marker for rapid intraoperative localization of nonpalpable tumors: a pilot study in a swine colorectal model. Surg Endoscopy, Online, 2003.

45. Blomquist JL, Van Rooyen JB, Cundiff GW, Kaufman HS. Practice patterns for vaginal hysterectomy and pelvic organ prolapse surgery. J of Pelvic Medicine & Surgery 9(4), 2003.

46. Lake JP, Ortega A, Vukasin P, Kaiser AM, Kaufman HS, Beart RW. Internet use by colorectal surgery patients: A surgeon's tool for education and marketing. Am Surg 70(6):553-8, 2004.

Non Peer Review Articles

1. Frasca P and Kaufman HS: Asbestos analysis by SEM of air samples during and after removal operations. Proc. Workshop on the Monitoring and Evaluation of Airborne Asbestos Levels following an Abatement Program. 225-232, 1985.

Articles In Press

1. Choti MA, Kaufman HS. Prognostic Significance of Molecular Margin Status in Patients Undergoing Resection for Rectal Cancer. Ann Surg, 2003.

2. DeMeester SL, Pannu H, Cundiff G, Buller J, Bluemke D, Kaufman HS. Rectocele is predictive of occult levator ani hernia: A dynamic MR imaging study. Dis Colon Rectum.

Articles Submitted

1. Kaufman HS, Cundiff GW, Buller JL, Thompson JR, DeMeester SL, Rychcik JL, Genadry RR. Suture rectopexy and sacral colpoperineopexy with AllodermÒ for perineal descent.

2. Kaufman HS, Heath EI, Forastiere AA, Heitmiller RF, Szabo Z, Yang S, Wu TT, Kleinberg L, OluKayod K, Talamini MA. Laparoscopy is superior to PET scanning for the diagnosis of intraabdominal regional metastases in patients with distal esophageal cancer.

3. DeMeester SL, Pannu H, Cundiff G, Buller J, Blueneke D, Kaufman HS. Perineal Descent is predictive of occult levator ani hernia: A dynamic MR-Imaging study.

Book Chapters:

1. Kaufman HS. Anal Fissure. In Cameron. JL, (ed): Current Surgical Therapy VI. 272-274, 1998.

2. Kaufman HS and Cameron JC. Small Bowel Neoplasms. In Fazio VW and Church JM, (eds): Current Therapy in Colon and Rectal Surgery, 2E. (Submitted).

3. Goldin SB, Harmon JW, Kaufman HS. Colon. In Gordon T and Cameron JL (eds): Evidence Based Surgery. 274-299, 2000.

4. Sonnenday CJ, Kaufman HS. Diverticulitis: The Practice of General Surgery, 1E. 503-509, 2002

5. Kaufman HS, Harris ML. Crohn’s Disease: General Considerations, Presentation, Diagnosis, and Medical Management: In Zuidema GD, Yeo CY (eds): Surgery of the Alimentary Tract, 5th ed. 377-390, 2002.

6. Lillemoe KD and Kaufman HS. Small Bowel Neoplasms. In Zuidema GD, Yeo CY (eds): Surgery of the Alimentary Tract, 5th ed. 358-375, 2002.

7. Kaufman HS. Colon Cancer. In Cameron. JL, (ed): Current Surgical Therapy VII. 229-235, 2001.

8. Kaufman HS. Surgical Therapy: Colonic and Anorectal. In Schuster M. (ed): Atlas of Gastrointestinal Motility. 445-462, 2002.

9. Ellerkmann M and Kaufman HS. Defecatory dysfunction in: Ostergard’s Urogynecology and Pelvic Floor Disorders, 5th ed., 2002.

10. Kaufman HS and Wasserberg N. Hemorrhoids. In Bayless TM and Diehl AM (eds), Advanced Therapy in Gastroenterology and Liver Disease, 5th ed., 2004.

11. Kaufman HS. Rectal Prolapse. In Schulick RD and Lillemoe KD (eds): Pocket General Surgery, 2004.

12. Kaufman HS. Hemorrhoids. In Schulick RD and Lillemoe KD (eds): Pocket General Surgery, 2004.

Abstracts and Letters:

1. Frasca P, Soriano R, Jankowski D, and Kaufman HS: Extracellular lipids in human cortical bone. Proc ORS 29:19, 1983.

2. Loewy AG, Wilson FJ, Taggart NM, Frasca P, and Kaufman HS: A covalently cross-linked matrix in the myofibrils of skeletal muscle. Fed Proc 42:2213, 1983.

3. Loewy AG, Wilson FJ, Taggart NM, Greene EA, Frasca P, and Kaufman HS: Covalently cross-linked matrixes in chicken pectoral muscle. J. Cell Biol 83:274a, 1983.

4. Frasca P, Soriano R., Jankowski D, and Kaufman HS: Bone matrix lipid: Origin and ultrastructure. Proc ORS 30, 1984.

5. Magnuson TH, Webb TH, Lillemoe KD, Peoples GE, Kaufman HS, Watt PC, and Pitt HA: Leucine-enkephalin increases prairie dog sphincter of Oddi activity. Gastroenterology 94:A277, 1988.

6. Lillemoe KD, Magnuson TH, Webb TH, Kaufman HS, Watt PC, D'Souza MP, and Pitt HA: Bilirubin monoglucuronide promotes cholesterol gallstone formation. Hepatology 8:1373, 1988.

7. D'Souza MP, Magnuson TH, Kaufman HS, Lillemoe KD, and Pitt, HA: Biliary glycoproteins in patients with cholesterol stones, pigment stones, and no gallstones. Gastroenterology 94:A536, 1988. (Presented at the American Gastroenterological Association, 1991).

8. Kaufman HS, Magnuson TH, Lillemoe KD, Frasca P, and Pitt HA: Windowless energy dispersive x-ray microanalysis of gallstones. Gastroenterology, 96:A612, 1989. (Presented at the American Gastroenterological Association, 1991).

9. Ahrendt SA, Kaufman HS, Pitt HA, Lillemoe KD: Octreotide inhibits and CCK stimulates prairie dog sphincter of Odd motility via noncholinergic pathways. Gastroenterology 100:A307, 1991. (Presented at the American Gastroenterological Association, 1991).

10. Kaufman HS, Lillemoe KD, Magnuson TH, Ahrendt SA, Frasca P, Pitt HA: Calcium salts differ among variable-sized cholesterol gallstones from individual patients. Gastroenterology 100:A759, 1991. (Presented at the American Gastroenterological Association, 1991).

11. Lipsett PA, Kaufman HS, Lillemoe KD, Pitt HA: Unique nonmucin glycoproteins are present in cholesterol and pigment gallstones. Gastroenterology 100:A767, 1991. (Presented at the American Gastroenterological Association, 1991).

12. Ahrendt SA, Fox-Talbot K, Kaufman HS, Lillemoe KD and Pitt HA: The effect of dietary fish oil on cholesterol carriers in bile. Gastroenterology 100:A713, 1991. Lipsett PA,

13. Lipsett PA, Kaufman HS, Lillemoe KD, Pitt HA: Nonmucin glycoproteins are similar in hepatic and gallbladder bile in patients with cholesterol gallstones. Hepatology 14:265 (A), 1991.

14. Kaufman HS, Lipsett PA, Ahrendt SA, Frasca P, Pitt HA, and Lillemoe KD: Identification of a protein skeleton in cholesterol gallstones. Gastroenterology 102:A317, 1992. (Presented at the American Gastroenterological Association, 1992)

15. Lipsett PA, D'Souza MP, Kaufman HS, Magnuson TH, Fox-Talbot MK, Lillemoe KD, and Pitt HA. Differences in biliary glycoprotein nonmucin glycoproteins in patients with and without gallstones. Gastroenterology 102:A319, 1992. (Presented at the American Gastroenterological Association, 1992).

16. Lipsett PA, Kaufman HS, Shermak MA, Fox-Talbott MK, Lillemoe KD, and Pitt HA. Early appearance of biliary nonmucin glycoproteins in cholesterol-fed prairie dogs. Gastroenterology 102:A320, 1992. (Presented at the American Gastroenterological Association, 1992).

17. Ahrendt SA, Fox-Talbott MK, Kaufman HS, Lillemoe KD, and Pitt HA: A novel cholesterol carrier helps prevent crystal precipitation. Gastroenterology 102:A772, 1992.

18. Lipsett PA, Hildreth JE, Kaufman HS, Lillemoe KD, and Pitt HA: Pronucleating glycoproteins in gallstones are immunoglobulin fragments. Gastroenterology 102:A844, 1992. (Presented at the American Gastroenterological Association, 1992).

19. Shermak MA, Lipsett PA, Kaufman HS, Fox-Talbott MK, Pitt HA, and Lillemoe KD: Calcium interacts with biliary proteins to induce cholesterol crystal nucleation. Gastroenterology 102:A941, 1992. (Presented at the American Gastroenterological Association, 1992).

20. Kaufman HS, Lillemoe KD, Mastovich JT, and Pitt HA. Environmental scanning microscopy of fresh human gallstones reveals new morphologies of precipitated calcium salts. In Baily GW, Bently J, and Small JA (ed): Proc. 50th Annual Meeting of the Electron Microscopy Society of America. San Francisco, CA, San Francisco Press, pp 1322-1323, 1992. (Presented at the Electron Microscopy Society of America, 1992).

21. Lipsett PA, Falconer SD, Kaufman HS, Fox-Talbot MK, Lillemoe KD, and Pitt HA: Cholesterol feeding alters nonmucin glycoproteins in gallbladder and hepatic bile. Gastroenterology 104:A942, 1993. (Presented at the American Gastroenterologic Association, 1993).

22. Lipsett PA, Falconer SD, Kaufman HS, Fox-Talbot MK, Lillemoe KD, and Pitt HA: Immunoglobulin-antigen complexes from gallstones are potent pronucleators of cholesterol. Gastroenterology 104:A942, 1993. (Presented at the American Gastroenterologic Association, 1993).

23. Micali S, Silver RI, Kaufman HS, Moore RG, Marley G, Partin AW, Kavoussi LR, Docimo SG: Laparoscopic oliguria: assessment of ischemic renal tubular injury by urinary N-Acetyl, Beta-D-glucosaminidase. J. Endourol, 10:S63, 1996.

24. Kaufman HS and Lillemoe KD: Letter of response. Hepatology 23:1286-1287,1996.

25. Micali S, Silver RI, Kaufman HS, Douglas VD, Marley G, Partin AW, Moore RG, Kavoussi LR, Docimo SG: Is laparoscopic oliguria an ischemic phenomenon? Measurement of urinary n-acetyl-B, D-glucosaminidase levels. J Urol, 157, no. 4 suppl.:402, 1997.

26. Murray K, Frasca P, Pitt HA, Lipsett PA, Lillemoe KD, Kaufman HS: Iron and copper are preferentially precipitated in the cores of cholesterol gallstones. Gastroenterology 112:A518,1997. Gastroenterology 112:A518,1997. (Presented at the American Gastroenterological Association, 1997).

27. Sohn TA, Lillemoe KD, Yeo CJ, Pitt HA, Kaufman HS , Hruban RH, Cameron JL: Adenocarcinoma of the duodenum: the influence of site on survival. Gastroenterology 112:A1474, 1997. ( Presented at The Society for Surgery of The Alimentary Tract, 1997)

28. Talamini M, Kutka M, Heitmiller R, Kaufman HS, Flood W, Forastiere A: Laparoscopic staging of esophageal cancer alters neoadjuvant therapy. Gastroenterology 112:A1478, 1997. (Presented at The Society for Surgery of The Alimentary Tract, 1997)

29. Talamini MA, Moesinger RC, Kaufman HS, Kutka M, Harris M, Bayless T: Laparoscopic assisted bowel resection for Crohn’s disease: The best of both worlds. Gastroenterology 112:A1478, 1997. (Presented at The Society for Surgery of The Alimentary Tract, 1997).

30. Murray KP, Kaufman HS, Shin JH, Laraia P, Frasca P, Lipsett PA, Lillemoe KD, Pitt HA. Pigment and cholesterol gallstones differ in their biometal content. Gastroenterology 114:A533, 1998. (Presented at American Gastroenterological Association, 1998).

31. Kaufman HS, Murray KP, Shin JH, Frasca P, Laraia P, Lipsett PA, Lillemoe KD, Pitt HA. Transition metals are preferentially precipitated in the cores of solitary cholesterol gallstones. Gastroenterology, 114:A526, 1998. (Presented at the American Gastroenterological Association, 1998).

32. Kutka MF, Talamini MA, Kaufman HS, Poulose BK, Moesinger RC. Laparoscopic bowel resection in Crohn’s patients offers many advantages over open surgery. Gastroenterology 114:A1403, 1998. (Presented at the Society for Surgery of the Alimentary Tract, 1998)

33. Kaufman HS, Kahn A, Iacobuzio-Donahue C, Talamini M, Lillemoe K. Hamilton S. Aggressive management of cytomegalovirus (CMV) enterocolitis improves survival. Dis Colon Rectum 41:A19, 1998. (Presented at the American Society of Colon and Rectal Surgeons, 1998).

34. Pannu HK, Bluemke DA, Kaufman HS, Fishman EK. Dynamic MR imaging of the pelvic floor: Correlation with surgical findings. Am J Roentgenol Suppl 1999; 172(3):132.

35. Hsieh G, Thompson JR, Buller JL, Kaufman HS, Gordon T.A., Cundiff GW. Case volume and outcomes in reconstructive pelvic surgery for pelvic organ prolapse. Int Urogyn J 1999; 10 :S38. (Presented at the American Urogynecology Association, 1999)

36. Cundiff GW, Hsieh G, Gordon TA., Buller J, Thompson J, Kaufman HS. Practice patterns for hysterectomy and pelvic organ prolapse surgery. Int Urogyn J 1999; 10:S42. (Presented at the American Urogynecology Association, 1999).

37. Kaufman HS, Thompson J, Pannu H, Genedry R, Bluemke D, Jones B, Cundiff G. Dynamic pelvic magnetic resonance (MR) imaging and cystoproctograpy alter surgical management of pelvic floor disorders. Dis Colon Rectum 2000; 43:A15. (Presented at the Annual Meeting of the American Society of Colon and Rectal Surgeons, 2000).

38. Kaufman HS, Cundiff G, Thompson J, Van Rooyen J, Rychcik J, Genedry R. Suture rectopexy and sacral colpoperineopexy with Alloderm. Dis Colon Rectum 2000; 43: A16. (Presented at the Annual Meeting of the American Society of Colon and Rectal Surgeons, 2000).

39. DeMeester S, Pannu H, Cundiff G, Buller J, Bluemke D, Kaufman HS. Rectocele is predictive of occult levator ani hernia: Dynamic Magnetic Resonance Imaging Study. Dis Colon Rectum 2000;43:A37. (Presented at the Annual Meeting of the American Society of Colon and Rectal Surgeons, 2000).

40. Bristow RE, Smith Sehdev AE, Kaufman HS, Kurman RJ, Montz FJ. Ablation of metastatic ovarian carcinoma with the argon beam coagulation. Pathologic analysis of tumor destruction. Presented at the Thirty-Second Annual Meeting of the Society of Gynecologic Oncologists 2001).

41. Morren GL, Ryn AK, Hallbook O, Sjodahl R. Invited commentary by Kaufman HS. Clinical measurement of pelvic floor movement: Evaluation of a new device. Dis Colon Rectum 2004. (Submitted for publication)

Other National and International Presentations and Visiting Lectures:

1. Determination of the Organic Calcium Salt Composition of Human Gallstones by Backscattered Electron Imaging and Windowless Energy Dispersive X-ray Microanalysis. Great Lakes Electron Microscopy Association, 1991.

2. Postoperative follow-up for Colorectal Cancer. The Johns Hopkins Medical Institutions Twenty-Second Annual Topics in Gastroenterology and Liver Disease, 1996.

3. Surgical Options for Anorectal Problems. The Johns Hopkins International Symposium on Gastrointestinal Motility Disorders, 1997.

4. Current Surgical Approaches for Colorectal Cancer. The Johns Hopkins Oncology Center’s 23rd Annual Symposium on Diagnosis and treatment of Neoplastic Disorders, 1997.

5. Surgical Approaches for Colorectal Disorders. The Johns Hopkins Medical Institutions Twenty-Third Annual Topics in Gastroenterology and Liver Disease, 1997.

6. Management of Rectal Cancer. John R. Marsh Oncology Symposium, Washington County Hospital. Hagerstown, MD, 1997.

7. Multimodality Therapy for Rectal Cancer. St. Joseph’s Hospital. Towson, MD, 1997.

8. Surgical Management of Anal Incontinence. The Johns Hopkins Medical Institutions Fifteenth Annual Houston Everett Memorial Course in Urogynecology, 1998.

9. Multimodality Therapy for Rectal Cancer. The Johns Hopkins Medical Institutions Twenty-Fourth Annual Topics in Gastroenterology and Liver Disease, 1998.

10. Surgical Management of Anal Incontinence. The Johns Hopkins Medical Institutions Sixteenth Annual Houston Everett Memorial Course in Urogynecology, 1999.

11. Small Bowel Obstruction Following Colorectal Surgery: Etiology and Prevention. Third International Colorectal Symposium, Zakopane, Poland, 1999.

12. Multimodality Therapy for Rectal Cancer. Third International Colorectal Symposium, Zakopane, Poland, 1999.

13. Multimodality Therapy for Rectal Cancer. King Fahd National Guard Hospital, Riyadh, Saudi Arabia, 1999.

14. Postoperative Follow-up for Colorectal Cancer. The Johns Hopkins Medical Institutions Twenty-Fifth Annual Topics in Gastroenterology and Liver Disease, 1999.

15. Advances in the Diagnosis and Management of Perineal Descent. Visiting Professor of Surgery, Washington Hospital Centers, Washington, DC, 1999.

16. Surgical Management of Anal Incontinence. The Johns Hopkins Medical Institutions Seventeenth Annual Houston Everett Memorial Course in Urogynecology, 2000.

17. Advances in the Evaluation and Management of Perineal Descent. The Johns Hopkins Medical Institutions Twenty-Fifth Annual Topics in Gastroenterology and Liver Disease, 2000.

18. Strategies for Perioperative Nutrition. The Johns Hopkins Medical Institutions, Marco Island, Florida and Aspen, Colorado, 2000.

19. Patient Selection, Preparation and Complications of Laparoscopic Surgery. The Johns Hopkins Medical Institutions, Marco Island, Florida and Aspen, Colorado, 2000.

20. Dynamic Imaging of Pelvic Floor Disorders. Turnbull Symposium. The Cleveland Clinic, Cleveland, OH, 2000.

21. Advances in the Surgical Management of Perineal Descent, Turnbull Symposium, The Cleveland Clinic, Cleveland, Ohio, 2000.

22. The Surgical Management of Constipation and Rectal Prolapse, The American Urogynecologic Society Annual Meeting, Postgraduate Course in Defecatory Dysfunction, Hilton Head Island, SC, 2000.

23. Pathophysiology of Fecal Incontinence, The American Urogynecologic Society Annual Meeting, Postgraduate Course in Defecatory Dysfunction, Hilton Head Island, SC, 2000.

24. Video Presentation: Surgical Management of Rectal Prolapse, The American Urogynecologic Society Annual Meeting, Postgraduate Course in Defecatory Dysfunction, Hilton Head Island, SC, 2000

25. Small Bowl Obstruction: Etiology, Economic Impact, and Strategies for Prevention. St. Joseph’s Hospital, Towson, MD, 2000.

26. The Surgical Management of Inflammatory Bowel Disease. The Crohn’s and Colitis Foundation, Columbia, MD, 2000.

27. Small Bowl Obstruction: Etiology, Economic Impact, and Strategies for Prevention. Al Hamadi Hospital, Riyadh, Saudi Arabia, 2001.

28. Surgical Management of Perineal Descent. The Johns Hopkins Medical Institutions Eighteenth Annual Houston Everett Memorial Course in Urogynecology, 2001.

29. Advances in the Evaluation and Management of Perineal Descent. St. Agnes Hospital, Baltimore, MD, 2001.

30. Advances in the Evaluation and Management of Pelvic Floor Disorders. The Johns Hopkins Medical and Surgical Association Biennial Meeting, 2001.

31. Virtual Colonoscopy. SAGES, SSAT joint symposium. 2001 Clinical Congress, American College of Surgeons, New Orleans, LA, 2001

32. Recurrent Fecal Incontinence and Perineal Descent. The Johns Hopkins Medical Institutions Nineteenth Annual Houston Everett Memorial Course in Urogynecology, 2002.

33. Greatest Hits Presentation, Genetics/Tumor Biology of Colorectal Cancer. ASCRS, New Orleans, LA, 2003.

34. Prevention of Post Operative Bowel Obstructions. Canadian Surgery Forum, Vancouver, BC, 2003.

35. Management of Enterocutaneous Fistula. Canadian Surgery Forum, Vancouver, BC, 2003.

36. Multimodality Therapy for Rectal Cancer. Grand Rounds, Surgical Education at Huntington Memorial Hospital, Pasadena, CA 2004.