Azathioprine (Imuran)
Purpose:
Azathioprine is given with other immunosuppressants to help prevent rejection of the new liver. It may be used for long-term (perhaps lifetime) immunosuppression.
How to take:
- Tablets - 50 mg; liquid - 10 mg per mL. IV Azathioprine may be given for the first few days after transplantation.
- The transplant team will determine the dosage appropriate for each patient based on weight and white blood cell count.
Precautions:
- Azathioprine may lower white blood cell and platelet counts. The patient should report any unusual bruising or bleeding to the transplant team.
- The benefits of taking this medication if a patient is pregnant or breast feeding must be weighed against the potential hazards to her, her fetus, or her infant. A patient should consult her transplant team immediately if she thinks she's pregnant.
Principal side effects:
These include, but are not limited to, nausea, vomiting, and reduced white blood cells and/or platelets.