Removal of cancer of the liver
by surgical means is the treatment of choice. In many patients surgery
is not possible because of the extent of the tumor or the presence of
cirrhosis that poses an excessive risk of liver failure after the surgery.
Radiofrequency ablation (RFA) is a procedure used to destroy (kill) liver
cancer.
RFA is frequently an option in patients in whom surgical removal
of the tumor is not an option. Radiofrequency ablation is a safe
and well tolerated procedure that is associated with few complications.RFA
is not currently viewed as curative procedure, rather is a procedure that
could lead to increased survivability and quality of life.
All patients being considered for RFA should be evaluated
by an experienced liver surgeon first since surgical removal of the tumor
is the best approach.
What is radiofrequency ablation?
Radiofrequency ablation begins with the passing of alternating electrical
current (radiofrequency energy) through the tumor tissue (lesion). Heat
is generated at the site of the lesion by this alternating current. This
heat produces coagulation and cellular destruction (necrosis or death),
resulting in ablation (destruction) of the tumor tissue.With the newer
RFA devices the thermal energy (heat) is evenly distributed to the lesion
in a consistent manner, causing consistent and complete tumor cell destruction.
How does it work?
Using intraoperative imaging of the tumor with ultrasound, an electrode
is positioned strategically within the lesion. Then, the electrode is
connected to a unique radiofrequency generator and electrical current
is delivered into the tissue. As the cells are heated, they are destroyed.
The mechanism of RFA is similar to that of a microwave oven, heating from
the inside out. The body eliminates the destroyed tumor cells over a period
of time.
How is the procedure performed?
RFA may be performed through an open surgical incision or via laparoscopy.
Laparoscopy (also referred to as minimally invasive surgery) is performed
through multiple, small skin incisions. At USC Dilip Parekh
M.D. has developed specialized techniques for performing RFA by laparoscopic
surgery. All patients are evaluated for the laparoscopic approach. Open
surgery is performed uncommonly for RFA. Your doctor will
discuss the best approach for your particular case.
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