Melanie Goldfarb, MD

• Evaluation and Management of Pediatric Thyroid Nodules
  InTech, March 2012
  View/download PDF file, 308KB
  
• Serving Adolescents and Young Adults: What We're Doing at USC and Other Institutions in the U.S.
  Presented by Dr. Melanie Goldfarb
  View/download Powerpoint Presentation (.pptx file, 3.32MB)
• Normocalcemic parathormone elevation after successful parathyroidectomy:
  Long-term analysis of parathormone variations over 10 years
  Surgery, September 2011
  The long-term significance of normocalcemic parathormone elevation (NPE) after successful parathyroidectomy for sporadic primary hyperparathyroidism remains unclear.
  View/download PDF file, 134KB
• Surgeon-performed ultrasound can predict benignity in thyroid nodules
  Surgery, September 2011
  Up to 70% of people may harbor thyroid nodules on routine screening.1 This includes the increasing number of patients referred for nonpalpable thyroid nodules found incidentally on imaging studies for other unrelated health issues.
  View/download PDF file, 236KB
• Resident/fellow assistance in the operating room for endocrine surgery in the era of fellowships
  Surgery, December 2010
  Historically, a high percentage of endocrine surgical procedures are performed by general
  surgeons in nonteaching environments. With the institution of accredited fellowships, we sought to
  determine whether that dynamic is changing.
  View/download PDF file, 127KB
• Minimally invasive surgery and cancer: controversies part 1
  Surgical Endoscopy, 2010
  Perhaps there is no more important issue in the care of surgical patients than the appropriate use of minimally invasive surgery (MIS) for patients with cancer. Important advances in surgical technique have an impact on early perioperative morbidity, length of hospital stay, pain management, and quality of life issues, as clearly proved with MIS. However, for oncology patients, historically, the most important clinical questions have been answered in the context of prospective randomized trials.
  View/download PDF file, 616KB
• Medical and Surgical Risks in Thyroid Surgery: Lessons from the NSQIP
  Annals of Surgical Oncology, February 2010
  To assess whether perioperative surgical outcomes associated with thyroid operations were different
  in those with benign or malignant conditions, we queried the NSQIP, a multi-institutional, risk-adjusted, prospective U.S. database.
  View/download PDF file, 566KB
• Synchronous parathyroid carcinoma, parathyroid adenoma, and papillary thyroid carcinoma in a patient with severe and longstanding hyperparathyroidism
  Endocr Pract. 2009 ; 15(5): 463–468. doi:10.4158/EP09075.CRR.
  Primary hyperparathyroidism (HPT) is caused by parathyroid carcinoma in less than 1% (1,2). Coexistent thyroid carcinoma in these patients is extremely rare, and to our knowledge, only 5 patients with documented synchronous parathyroid and thyroid carcinomas have been reported (3-7).
  View/download PDF file, 2.95MB

Stephen F. Sener, MD

• Ductal Carcinoma In Situ (DCIS) of the Breast: Perspectives on Biology and Controversies in Current Management
  Journal of Surgical Oncology, 2012
  With the implementation of widespread screening mammography in the 1980s and the increasing use of highly sensitive imaging modalities, such as magnetic resonance imaging (MRI), the incidence of
  ductal carcinoma in situ (DCIS) has increased considerably over the past several decades. Thus, there are pressing questions regarding optimal management.
  View/download PDF file, 111KB
• Accuracy of Predicting Axillary Lymph Node Positivity by Physical Examination, Mammography, Ultrasonography, and Magnetic Resonance Imaging
  Annals of Surgical Oncology, January 2012
  Axillary lymph node status continues to be among the most important prognostic variables regarding
  breast cancer survival. We were interested in our ability to accurately predict axillary nodal involvement by using physical examination and standard breast imaging studies in combination.
  View/download PDF file, 271KB
• Neoadjuvant Therapy for Breast Cancer
  Journal of Surgical Oncology, 2010
  The past few decades have seen an increase in both the role and the complexity of neoadjuvant therapy for breast cancer. Neoadjuvant therapy was initially described as systemic chemotherapy for inflammatory or locally advanced breast cancer but now entails a combination of chemotherapy, endocrine therapy, and targeted therapy.
  View/download PDF file, 116KB
• The effects of hormone replacement therapy on postmenopausal breast cancer biology and survival
  The American Journal of Surgery, 2009
  The goal of this study was to compare the characteristics of breast cancers and survival rates in HRT users versus nonusers.
  View/download PDF file, 88KB
• Neoadjuvant Therapy for Locally Advanced Cancer
  Journal of Surgical Oncology, November 2009
  Neoadjuvant therapy was initially designed to preoperatively treat locally advanced cancers with chemotherapy, but contemporary concepts have come to include chemo-, radiation, endocrine, and
  targeted therapies. In addition to impacting the options for surgical treatment, either by facilitating organ-preserving resection or by rendering a tumor resectable at all, neoadjuvant therapy has other potential benefits.
  View/download PDF file, 33KB
• Melanoma: Clinical Practice Guidelines in Oncology
  Journal of the National Comprehensive Cancer Network, March 2009
  In 2008, an estimated 62,480 new cases of melanoma will have been diagnosed and approximately 8420
  patients will have died of the disease in the United States.1 However, these projections for new cases
  may represent a substantial underestimation, because many superficial and in situ melanomas treated in the outpatient setting are not reported.Description
  View/download PDF file, 1.66MB
• Survival rates for breast cancers detected in a community service screening mammogram program
  American Journal of Surgery, August 2005
  From 1994 through 2001, data on 1237 patients with breast cancer were collected concurrent with definitive surgical treatment and entered into a comprehensive database.
  View/download PDF file, 111KB